By Steve Elliott of Toke of the Town
A marijuana component helps mitigate cocaine addiction in mice, according to a new study, lending further evidence to the notion that marijuana is an “exit” drug and could become the next big anti-addiction therapy.
The discovery by researchers in China and Maryland was announced in the July 2011 issue of Nature Neuroscience magazine, reports Stephen C. Webster at The Raw Story.
Cannabidiol (CBD), a medically useful component of marijuana that does not produce a “high,” effectively turns down a receptor in the brain that is stimulated by cocaine, the study found.
Scientists used a synthetic version of cannabidiol, called JWH-133, to see how mice given regular doses of cocaine might respond. The found the mice dramatically reduced their intravenous cocaine intake — by up to 60 percent — after being given JWH-133.
“It’s a very significant reduction,” said Zheng-Xiong Xi, the lead author of the study and a researcher at the National Institute on Drug Abuse (NIDA), reports Maia Szalavitz at Time.
“It’s extremely exciting,” said Antonello Bonci, scientific director for intramural research at NIDA.
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